The role played by alternative splicing in antigenic variability in
Por um escritor misterioso
Last updated 28 março 2025

Endo-parasites that affect humans include Plasmodium, the causative agent of malaria, which remains one of the leading causes of death in human beings. Despite decades of research, vaccines to this and other endo-parasites remain elusive. This is in part due to the hyper-variability of the parasites surface proteins. Generally these surface proteins are encoded by a large family of genes, with only one being dominantly expressed at certain life stages. Another layer of complexity can be introduced through the alternative splicing of these surface proteins. The resulting isoforms may differ from each other with regard to cell localisation, substrate affinities and functions. They may even differ in structure to the extent that they are no longer recognised by the host’s immune system. In many cases this leads to changes in the N terminus of these proteins. The geographical localisation of endo-parasitic infections around the tropics and the highest incidences of HIV-1 infection in the same areas, adds a further layer of complexity as parasitic infections affect the host immune system resulting in higher HIV infection rates, faster disease progression, and an increase in the severity of infections and complications in HIV diagnosis. This review discusses some examples of parasite surface proteins that are alternatively spliced in trypanosomes, Plasmodium and the parasitic worm Schistosoma as well as what role alternate splicing may play in the interaction between HIV and these endo-parasites.

Immunoglobulin germline gene variation and its impact on human

Regulatory roles and mechanisms of alternative RNA splicing in

Dysregulation and therapeutic targeting of RNA splicing in cancer

Cancers, Free Full-Text

Alternative splicing in aging and longevity

Immuno Flashcards

The role played by alternative splicing in antigenic variability in

Alternative splicing of cell surface receptors in Homo sapiens

Frontiers Correlations Between the Characteristics of

Telomere and Subtelomere R-loops and Antigenic Variation in

Non‐coding RNAs in malaria infection - Lodde - 2022 - WIREs RNA

Alternative splicing - Wikipedia

Expression of human IgD by alternative splicing and CSR (A) Ig
Recomendado para você
-
SCP-7147 - SCP Foundation28 março 2025
-
Scaling SCP-001 Atonement. #fypシ #fyp #viral #scp #scpfoundation28 março 2025
-
3581 Norton Ave APT 4, Lynwood, CA 9026228 março 2025
-
Dragons Great Hall in Environments - UE Marketplace28 março 2025
-
Terry Hasty - Vice-President - MindSpring Consulting28 março 2025
-
UTG 3-12X44 30mm Compact Scope w/ AO/ 36-color Glass Mil-dot28 março 2025
-
New 30-40cm Anime Scp Siren Head Plush Doll Toys Foundation Scary28 março 2025
-
Synthesis of the Tetrahydroisoquinoline Alkaloid (±)-Renieramycin28 março 2025
-
Cross Reference List Tax Parcels --- Owner Name Order28 março 2025
-
The role played by alternative splicing in antigenic variability28 março 2025
você pode gostar
-
Anime picture rakudai kishi no cavalry 600x843 494725 en28 março 2025
-
Arbitragem e Ensino de Xadrez: Ruy Lopez de Segura28 março 2025
-
Baixe Bolo Padaria Comprar Jogos no PC28 março 2025
-
Blox Fruits Script Pastebin 2022 – Page 17 – ScriptPastebin28 março 2025
-
Mine Jogos12328 março 2025
-
GSJ Toys Store - Mini Game Vintage :: Dragon Ball :: Dragon Star 🏷 [VENDIDO] #dragonball 🎮 Funcionando 🔋 Pilhas inclusas #gsjtoys #games28 março 2025
-
ps4 pro for Sale in Richmond, IN - OfferUp28 março 2025
-
BONECA POSSUÍDA HALLOWEEN C/ SOM E MOVIMENTO - BONECA POSSUÍDA28 março 2025
-
PLAYING ROBLOX GARTEN OF BANBAN 2 GAMES (surprisingly good28 março 2025
-
🤯O final da saga MAJIN BOO poderia ser DIFERENTE *entenda*28 março 2025