Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and Beyond
Por um escritor misterioso
Last updated 20 setembro 2024
Behavioral experiences can modulate neural networks through changes in synaptic morphology and number. In contrast, abnormal morphogenesis of dendritic spines is associated with cognitive impairment, as in Fragile X syndrome. Dendritic or synaptic protein synthesis could provide the specificity and speed necessary for spine morphogenesis. Here, we highlight locally translated proteins shown to affect synaptic morphology (e.g., Fragile X mental retardation protein).
Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic
Targeted treatments for fragile X syndrome
Frontiers Local Translation Across Neural Development: A Focus
Biomolecules, Free Full-Text
Dissociation of functional and structural plasticity of dendritic spines
Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic
Frontiers Homeostatic Roles of the Proteostasis Network in Dendrites
Pten heterozygosity restores neuronal morphology in fragile X
The fragile X mental retardation protein regulates tumor
Which Comes First in Fragile X Syndrome, Dendritic Spine
A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum
Dual Regulation of Fragile X Mental Retardation Protein by Group I
IJMS, Free Full-Text
Fragile X Syndrome - ScienceDirect
Depletion of the Fragile X Mental Retardation Protein in Embryonic
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