Cells, Free Full-Text
Por um escritor misterioso
Last updated 08 março 2025

The neurovascular unit (NVU) is a conceptual framework that has been proposed to better explain the relationships between the neural cells and blood vessels in the human brain, focused mainly on the brain gray matter. The major components of the NVU are the neurons, astrocytes (astroglia), microvessels, pericytes, and microglia. In addition, we believe that oligodendrocytes should also be included as an indispensable component of the NVU in the white matter. Of all these components, astrocytes in particular have attracted the interest of researchers because of their unique anatomical location; these cells are interposed between the neurons and the microvessels of the brain. Their location suggests that astrocytes might regulate the cerebral blood flow (CBF) in response to neuronal activity, so as to ensure an adequate supply of glucose and oxygen to meet the metabolic demands of the neurons. In fact, the adult human brain, which accounts for only 2% of the entire body weight, consumes approximately 20–25% of the total amount of glucose and oxygen consumed by the whole body. The brain needs a continuous supply of these essential energy sources through the CBF, because there are practically no stores of glucose or oxygen in the brain; both acute and chronic cessation of CBF can adversely affect brain functions. In addition, another important putative function of the NVU is the elimination of heat and waste materials produced by neuronal activity. Recent evidence suggests that astrocytes play pivotal roles not only in supplying glucose, but also fatty acids and amino acids to neurons. Loss of astrocytic support can be expected to lead to malfunction of the NVU as a whole, which underlies numerous neurological disorders. In this review, we shall focus on historical and recent findings with regard to the metabolic contributions of astrocytes in the NVU.

IJMS, Free Full-Text

STEM CELLS: Vol 35, No 5
Cell-free Macromolecular Synthesis

Iec/Ts 62886 Get File - Colaboratory

Amyloid β directly interacts with NLRP3 to initiate inflammasome activation: identification of an intrinsic NLRP3 ligand in a cell-free system, Inflammation and Regeneration
An illustration of the full-duplex cell-free massive MIMO system.

Rapid cell-free forward engineering of novel genetic ring oscillators

Improving cell-free glycoprotein synthesis by characterizing and enriching native membrane vesicles

Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation
Recomendado para você
-
I want my words and those of the law to meet on the page and touch”: On Alia Trabucco Zerán's When Women Kill - Asymptote Blog08 março 2025
-
Miriam Leitão é a +Premiada Jornalista da História na Região Sudeste08 março 2025
-
planejar_BANNERSITE-VIDEOCAST-ETICA-09-1.jpg08 março 2025
-
CIMB, Free Full-Text08 março 2025
-
2022 UC Santa Cruz Commencement Program 2 by UCSC08 março 2025
-
Cellulose Nanocrystals from Postconsumer Cotton and Blended08 março 2025
-
31jq7xT5B6L._CLa, 599,500, 51NC2RgLy4L.jpg,41OglMcD09L.jpg08 março 2025
-
Morsyleide ROSA, Senior Researcher, PhD08 março 2025
-
Live Updates & Results European Championships Black Belt Day 108 março 2025
-
2020 Oakland Zoo Impact Report by Oakland Zoo - Issuu08 março 2025
você pode gostar
-
Tom Ince stays with Blackpool, decides against joining Cardiff City08 março 2025
-
Buy Roblox Gift Card 1200 Robux (PC) - Roblox Key - EUROPE - Cheap - !08 março 2025
-
Five Nights at Candy's custom night APK (Android App) - تنزيل مجاني08 março 2025
-
Russia Flag Vector Icons free download in SVG, PNG Format08 março 2025
-
Pique-esconde com Luccas Neto (Em Portugues do Brasil08 março 2025
-
Marvel's Spider-Man Remastered Just Copied Miles Morales' Best Feature08 março 2025
-
Perfume Feminino Carolina Herrera Kit Good Girl Eau de Parfum 80Ml + Body Lotion 100M + Travel Size 10Ml - Del Mondo08 março 2025
-
coin master 15 free spin link of last 5 days in 202308 março 2025
-
Quintessential Set The Quintessential Quintuplets | Weiß Schwarz08 março 2025
-
arceus x new update 2022 v3 discord|TikTok Search08 março 2025