Cancers, Free Full-Text
Por um escritor misterioso
Last updated 17 março 2025

Ubiquitin-like, containing PHD and RING finger domain, (UHRF) family members are overexpressed putative oncogenes in several cancer types. We evaluated the protein abundance of UHRF family members in acute leukemia. A marked overexpression of UHRF1 protein was observed in ALL compared with AML. An analysis of human leukemia transcriptomic datasets revealed concordant overexpression of UHRF1 in B-Cell and T-Cell ALL compared with CLL, AML, and CML. In-vitro studies demonstrated reduced cell viability with siRNA-mediated knockdown of UHRF1 in both B-ALL and T-ALL, associated with reduced c-Myc protein expression. Mechanistic studies indicated that UHRF1 directly interacts with c-Myc, enabling ALL expansion via the CDK4/6-phosphoRb axis. Our findings highlight a previously unknown role of UHRF1 in regulating c-Myc protein expression and implicate UHRF1 as a potential therapeutic target in ALL.

Event-free Survival with Pembrolizumab in Early Triple-Negative

10 Year Cancer Survivor Card Remission Card Cancer Free Card

Cancer-Free with Food: A Step-by-Step by Werner Gray, Liana

The Cure for All Cancers - free download pdf - issuhub

ONE year and Cancer FREE!

Cancer Financial Support Organizations

Colorectal Cancer Awareness Month Graphics - National LGBT Cancer
Flow Cytometric Analysis Of Several Cancer Cell Lines Breast

Cancers, Free Full-Text

Remission, cancer-free, no evidence of disease: What's the
Recomendado para você
-
Old Rose Pink Tulle Dress - kids atelier17 março 2025
-
Goat Anti-Mouse IgG (H+L) Secondary Antibody, Cy3 Conjugated17 março 2025
-
Blue and white manga cover Photographic Print by mia-igg17 março 2025
-
Let's Dance Personalized Gifts Handmade Real Glass Neon17 março 2025
-
Inhibitory receptor FcγRIIb mediates the effects of IgG on a phagosome acidification and a sequential dephosphorylation system comprising SHIPs and Inpp4a - Tomohiro Segawa, Kaoru Hazeki, Kiyomi Nigorikawa, Atsuko Nukuda, Tomoki Tanizawa17 março 2025
-
Relative Increase in IgG Antibodies to Pseudomonas aeruginosa 60-kDa GroEL in Prediabetic Patients with Cystic Fibrosis17 março 2025
-
Dg Stock Vector Illustration and Royalty Free Dg Clipart17 março 2025
-
Resultados da busca por: 'luminaria de ch o piso igg ajustavel 210x20x24cm metal femarte 160490214 p', Inspire Home17 março 2025
-
Express Covid Test Igm Igg Antibodies Novel Coronavirus Sars Cov Stock Photo by ©anyaivanova@gmail.com 37779084617 março 2025
-
Be Notorious Greeting Cards by Laura Bolter17 março 2025
você pode gostar
-
Hunter x Hunter Figures - Anime Hunter x Hunter Figure Killua Zoldyck Gon Freecss Kurapika Hisoka Kulolo Lushilufelu Figurine AL270717 março 2025
-
Olympic Games Rio 2016 editorial stock photo. Image of pavilion - 9716004817 março 2025
-
VIVO 64 GB 12.0 - 15.9 MP Camera Resolution Cell Phones & Smartphones for sale17 março 2025
-
RollerCoaster Tycoon Touch17 março 2025
-
Image 5 - Basket Random - ModDB17 março 2025
-
Remedy Says Control Multiplayer Game and Max Payne Remakes Have Progressed to Production Stage17 março 2025
-
Faça download do arma de fogo jogos 3d fps jogo APK v2.6 para Android17 março 2025
-
Papel de parede : Doki Doki Literature Club, Monika Doki Doki Literature Club, Sasoura 1684x1191 - PPV - 1318405 - Papel de parede para pc - WallHere17 março 2025
-
GLAMORA WALLCOVERING GAUDIUM17 março 2025
-
EXERCICIOS 9º ANO NOTAÇÃO CIENTIFICA.docx, PDF, Terra17 março 2025