Cureus, Structural MRI Brain Alterations in Borderline Personality Disorder and Bipolar Disorder
Por um escritor misterioso
Last updated 28 março 2025

Bipolar disorder (BD) and borderline personality disorder (BPD) share many behavioral features, such as periods of marked affective lability and instability. Although there is a symptomatic overlap, the two disorders may be differentiated based on longitudinal course, phenomenology, and treatment responsiveness. In addition, the emotional changes in BPD are generally influenced by interpersonal factors, whereas BD episodes tend to be more sustained. We performed a literature review on the structural MRI features of both disorders and compared the findings. There are differences in areas of white and gray matter volumes and thickness in BP and BPD. BPD primarily affects the fronto-limbic network, in particular, the amygdala, hippocampus, and orbitofrontal cortex, whereas BP affects both cortical and subcortical areas. There are a limited number of large studies, and many studies examined in this review did not adjust for confounding factors or motion artifacts, which limit the utility of current data.

Structural brain abnormalities and suicidal behavior in borderline personality disorder. - Abstract - Europe PMC

PDF] Functional MRI Correlations in Women Diagnosed with Borderline Personality Disorder Exposed to Self-Harm Imagery

PDF] Neuroimaging and genetics of borderline personality disorder: a review.

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Frontiers Structural and Functional Connectivity of the Anterior Cingulate Cortex in Patients With Borderline Personality Disorder

PDF) Emotion dysregulation, impulsivity and anger rumination in borderline personality disorder: the role of amygdala and insula

Brain structure and symptom dimensions in borderline personality disorder, European Psychiatry

Cortical haemodynamic response during the verbal fluency task in patients with bipolar disorder and borderline personality disorder: a preliminary functional near-infrared spectroscopy study, BMC Psychiatry

Abnormalities in Cortical Gray Matter Density in Borderline Personality Disorder, European Psychiatry

Cortical thickness of autistic people : r/autism

Why is Borderline Personality Disorder (BPD) misinterpreted as Bipolar Disorder?, by Tabindah Waheed

Frontiers Structural Features Related to Affective Instability Correctly Classify Patients With Borderline Personality Disorder. A Supervised Machine Learning Approach
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